首页> 中文期刊> 《国际医药卫生导报》 >外伤性脑水肿无创动态监测的临床研究

外伤性脑水肿无创动态监测的临床研究

摘要

目的 探讨并评价"无创性脑电阻抗扰动系数测定"在脑外伤颅内压监测临床应用中的可行性.方法 分别测定20名健康志愿者和动态监测80例脑外伤患者的脑电阻抗扰动系数,观察其变化,通过多媒体图像分析系统计算头颅CT 上血肿和血肿周围水肿的体积,并进行相关分析.结果 ①健康志愿者左、右大脑半球脑电阻抗扰动系数一致,无明显差异.②脑外伤合并脑水肿患者的脑电阻抗扰动系数明显升高.随着脑水肿的加剧,颅内压增高,从脑电阻抗扰动系数可以容易反应出来;随着手术清除颅内血肿或保守治疗后颅内血肿的逐渐吸收,患者的康复,脑水肿缓解,颅内压逐渐降低.扰动系数逐步下降.患者伤后1、3天患者脑电阻抗扰动系数明显升高,到7天时脑电阻抗扰动系数逐步下降.结论 脑电阻抗扰动系数测定可较敏感地反映脑外伤患者脑水肿的变化.扰动系数越高,提示脑水肿越重.该方法为临床上进行动态、床旁连续无创性脑水肿监测提供了新的有意义的手段.%Objective To explore and evaluate the feasibility of the "non-invasive EEC disturbances Coefficient of Resistance" in use of the clinical application of the brain injury intracranial pressure monitoring. Method Measure and dynamic monitoring 20 healthy volunteers and 80 patients with traumatic brain injury in patients with disturbances of brain electrical impedance coefficient, to observe theri changes, through the multi-media image analysis system to calculate the head CT edema around the hematoma and hematoma volume, and do the correlation analysis.Result (①The brain electrical impedance coefficients of the Healthy volunteers' left and right brain is the same, no significant difference. ② Traumatic brain injury with cerebral edema in patients with disturbances of brain electrical impedance factor increased significantly. With the intensification of cerebral edema, increased intracranial pressure, from the brain electrical impedance coefficients can easily be reflected that with the surgical removal of intracranial hematoma or conservative treatment of intracranial to make the hematoma absorbed gradually, the patient's rehabilitation, to alleviate brain edema, cranial pressure gradually reduced, a gradual decline of the disturbance factor. 1,3 days after injury in patients with brain electrical impedance disturbance factor in patients significantly increased to 7 days a gradual decline coefficient of brain electrical impedance disturbance. Conclusion The brain electrical impedance measurement may be more sensitive to disturbance factors reflect the brain edema in patients with traumatic brain injury changes. The higher the disturbance factor, the more severe brain edema. The method for the clinical dynamic, continuous non-invasive with monitoring of cerebral edema provided a new and meaningful way.

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