Comparison of risk factors associated with sepsis between road traffic injuries and non-road traffic injuries in ICU patients with severe trauma

Xiao-Yuan Ma; Hua-Ping Liang; Huai-Jian Jin; Shao-Wen Cheng; Wan-Qi Tang; Wei Ma; Li Luo; Xue Yang; Qian Wang; Bin Wang

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Comparison of risk factors associated with sepsis between road traffic injuries and non-road traffic injuries in ICU patients with severe trauma

机译：重症ICU患者道路交通伤害与非道路交通伤害败血症危险因素比较

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Objective:To estimate the incidence and related risk factors of sepsis between road traffic injuries (RTIs) and non-RTIs.Methods:Clinical data of 339 patients with severe trauma who were admitted into ICU in both Third Affiliated Hospital of Army Military Medical University and ChongGang General Hospital from January 2012 to December 2015 were retrospectively analyzed.Twenty items of potential risk factors affecting sepsis were evaluated by univariate and multivariate Logistic Analysis with the purpose of drawing a comparison between RTI patients and non-RTI patients.Results:There were 154 cases of RTI and 185 cases of nonRTI entering the study period.The significant independent risk factor of sepsis in RTIs was SOFA 11 (0R=4.821;95％ CI=1.901-12.226;P=0.001).The significant independent risk factors of sepsis in non-RTIs were SOFA 11 (OR=12.410;95％ CI=2.559-60.185;P=0.002),trachcal intubation (OR=8.913;95％ CI=2.322-34.206;P=-0.001),APACHE Ⅱ 15 (0R=3.684;95％ CI=1.750-7.753;P=0.001).Conclusions:The clinical medical personnel should not give equal treatment to RTI patients and non-RTI patients admitted in ICU in that factors predicting sepsis within above two groups are different.The sample volume should be increased and validated in further prospective research.

机译：目的：评估道路交通伤害（RTIs）与非RTIS之间败血症的发生率及相关危险因素。方法：陆军军医大学第三附属医院和重症监护室收治的339例严重创伤患者的临床资料回顾性分析2012年1月至2015年12月在重庆市总医院进行的20项影响脓毒症的潜在危险因素，采用单因素和多因素Logistic分析对RTI患者和非RTI患者进行比较。结果：154例RTI病例和185例非RTI病例进入研究期。RTIs脓毒症的独立危险因素是SOFA 11（0R = 4.821; 95％CI = 1.901-12.226; P = 0.001）。非RTIs中的SOFA 11（OR = 12.410; 95％CI = 2.559-60.185; P = 0.002），气管插管（OR = 8.913; 95％CI = 2.322-34.206; P = -0.001），APACHEⅡ15（ 0R = 3.684; 95％CI = 1.750-7.753; P = 0.001）。用法：临床医务人员不应对入住ICU的RTI患者和非RTI患者给予同等的待遇，因为上述两组中预测败血症的因素不同。应增加样本量并进行进一步的前瞻性研究验证。

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《急性病杂志（英文版）》 |2018年第5期|191-196|共6页
作者
Xiao-Yuan Ma; Hua-Ping Liang; Huai-Jian Jin; Shao-Wen Cheng; Wan-Qi Tang; Wei Ma; Li Luo; Xue Yang; Qian Wang; Bin Wang;
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State Key Laboratory of Trauma, Burns and Combined Injury, First Department, Research Institute of Surgery, Third Affiliated Hospital of Army Military Medical University, Chongqing, PR China;

Department of Critical Care Medicine, ChongGang General Hospital, Chongqing, PR China;

State Key Laboratory of Trauma, Burns and Combined Injury, First Department, Research Institute of Surgery, Third Affiliated Hospital of Army Military Medical University, Chongqing, PR China;

State Key Laboratory of Trauma, Burns and Combined Injury, First Department, Research Institute of Surgery, Third Affiliated Hospital of Army Military Medical University, Chongqing, PR China;

State Key Laboratory of Trauma, Burns and Combined Injury, First Department, Research Institute of Surgery, Third Affiliated Hospital of Army Military Medical University, Chongqing, PR China;

Trauma Center, The First Affiliated Hospital of Hainan Medical University, Haikou, Hainan, PR China;

State Key Laboratory of Trauma, Burns and Combined Injury, First Department, Research Institute of Surgery, Third Affiliated Hospital of Army Military Medical University, Chongqing, PR China;

State Key Laboratory of Trauma, Burns and Combined Injury, First Department, Research Institute of Surgery, Third Affiliated Hospital of Army Military Medical University, Chongqing, PR China;

State Key Laboratory of Trauma, Burns and Combined Injury, First Department, Research Institute of Surgery, Third Affiliated Hospital of Army Military Medical University, Chongqing, PR China;

State Key Laboratory of Trauma, Burns and Combined Injury, First Department, Research Institute of Surgery, Third Affiliated Hospital of Army Military Medical University, Chongqing, PR China;

Department of Critical Care Medicine, ChongGang General Hospital, Chongqing, PR China;

Department of Critical Care Medicine, ChongGang General Hospital, Chongqing, PR China;

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Comparison of risk factors associated with sepsis between road traffic injuries and non-road traffic injuries in ICU patients with severe trauma

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