首页> 中文期刊> 《航空航天医学杂志》 >光学相干断层扫描在评估曲安奈德联合雷珠单抗治疗糖尿病性黄斑水肿疗效中的应用

光学相干断层扫描在评估曲安奈德联合雷珠单抗治疗糖尿病性黄斑水肿疗效中的应用

         

摘要

目的:探讨光学相干断层扫描技术( opticalcoherencetomography ,OCT)在评估曲安奈德( triamcinolo-neacetonide, TA )联合雷珠单抗(Lucentis,LU)治疗糖尿病性黄斑水肿(diabetic macular edema,DME)疗效中的应用。方法应用OCT及荧光素眼底血管造影( FFA)确诊180例DME患者并随机分为3组,给予TA、LU、TA/LU治疗,比较视力及黄斑中心视网膜厚度( centralmacularthickness , CMT )。结果本研究中各治疗方案治疗DME均取得良好疗效。其中,TA/LU联合治疗组CMT最低,唯有LU治疗组未发现眼压升高并发症。结论 TA、LU、TA/LU等治疗DME 均取得较好疗效,临床上应根据实际情况选择治疗策略。%Objective To study the optical coherence tomography in the evaluation of triamcinolone acetonide Lucen -tis the application of the treatment of diabetic macular edema curative effect .Methods The application of OCT and fluo-rescein fundus angiography (FFA) confirmed 180 cases of patients with DME and randomly divided into 3 groups, TA, LU, TA/LU was given center of visual acuity and macular retinal thickness .Results Various therapeutic regimen for DME has achieved good results .Among them, the TA/LU CMT minimum combined treatment group , only LU elevated iop complications are not found in treatment group .Conclusions The treatment such as TA , LU, TA/LU DME has a-chieved good curative effect , clinical should choose according to actual situation treatment strategy .

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