抑制性消减杂交技术(SSH)是近年来兴起的一种分离、克隆差异基因的新技术.系统阐述了该技术的原理和优缺点,综述了该技术在水产无脊椎动物差异表达基因筛选方面应用的研究进展,并对该领域面临的问题进行剖析.%Suppression subtractive hybridization (SSH) is one of the new technologies to isolate and clone differentially expressed transcripts in recent years. The principles and characteristics of SSH, the research advances in marine invertebrates and the problems we encountered to-day were systematically discussed.
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