[Objective] To discuss the safe dose of triehiorhpon, copper sulfate and ferrous sulfate mixture against Platichthys stellalus. [ Method] The acute toxicity of triehiorhpon, copper sulfate and ferrous sulfate mixture to Platichthys stellatus which was 18-21 cm in length and 194. 1 g in weight were determined in a 15 - 17 ℃. water bath with 3.0% -3.2% salinity. [Result] The semi-lethal concentration (LC50) of triehiorhpon to Platichthys stellatus at 24 h and 48 h were 3. 63 and 3. 31 mg/L,and its safe concentration(SC) was 0. 83 mg/L. At the same conditions, the semi-lethal concentration (LC50) of copper sulfate and ferrous sulfate mixture to Platichthys stellatus at 24 h and 48 h were 9.55 and 6. 92 mg/L, and its safe concentration (SC) was 1. 09 mg/L. The order of the toxicity of two drugs was as follows: triehiorhpon > copper sulfate and ferrous sulfate mixture. [Conclusion] The triehiorhpon, copper sulfate and ferrous sulfate mixture should be carefully used or applied at low concentrations for the diseases control of Plalichthys stellatus.%[目的]探讨敌百虫和硫酸铜与硫酸亚铁合剂2种防治药物对星斑川鲽(Platichthys stellatus)的安全用量范围.[方法]在水温15～17 cC、盐度3.0％～3.2％的条件下,分别测定了敌百虫、硫酸铜与硫酸亚铁合剂对体长18～21 cm、平均体重194.1 g的星斑川鲽的急性毒性.[结果]敌百虫对星斑川鲽24、48 h的LC50分别为3.63和3.31 mg/L,安全浓度为0.83 mg/L;硫酸铜与硫酸亚铁合剂对星斑川鲽24、48 h的LC50分别为9.55和6.92 mg/L,安全浓度为1.09 mg/L.根据安全浓度判断,星斑川鲽对2种药物的敏感性为:敌百虫＞硫酸铜与硫酸亚铁合剂.[结论]在星斑川鲽疾病防治过程中应慎用或者降低浓度使用敌百虫或硫酸铜与硫酸亚铁合剂.
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