[Objective]The aim of the study was to provide references for the application of medicines in the breeding of Lutjanus rivulatus.[ Method ]The acute toxicity and the joint toxicity of copper,zinc ,alone and in combination to Lutjanus rivulatus was investigated with the static test method. [ Result]The results showed that the safe concentrations of Cu2＋ to Lutjanus rivulatus was 0. 103 8 mg/L,and the safe concentrations of Zn2+ was 3. 347 8 mg/L. The LC50 of 24 h and 48 h for copper were 0.422 3 and 0. 395 2 mg/L respectively. And those for zinc were 15. 888 5 and 14.123 2 mg/L respectively. The joint toxicity of Cu2＋ and Zn2 ＋ on Lutjanus rivulatus was greater than predicted from the individual toxicities.[ Conclusion ] Cu2 + was drastic toxicant to lutjanus rivulatus and Zn2＋ was a low toxic. The joint toxicity caused synergetic action when Cu2+ and Zn2+ exist together.%[目的]为蓝点笛鲷人工育苗中药物的施用提供参考.[方法]采用半静水法生物测试,研究Cu、Zn对蓝点笛鲷急性毒性及联合毒性.[结果]Cu的安全浓度为0.103 8 mg/L;Zn的安全浓度为3.347 8 mg/L.Cu对蓝点笛鲷幼鱼24和48 h的LC分别为0.422 3、15.888 5 mg/L;Zn对蓝点笛鲷幼鱼24和48 h的LC分别为0.395 2、14.123 2 mg/L.等毒性配比的2种重金属离子混合液对蓝点笛鲷幼鱼的毒性大于单一毒性.[结论]Cu为剧毒物质,Zn为低毒物质,两者混合表现为协同作用.
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