The objective of the experiment is to study the effect of Qinyu San powder on chicken injected by Escherichia coli. Method:Two hundred 14-age chickens were divided into 5 groups. After injected by Esche-richia coli,chicken in group 1-4 were fed diets including 3. 0%,1. 5%,0. 7% and 0% Qinyu San,respec-tively. Group 5 was the control group which was not injected by bacteria. Result:The cure rate and efficacy in the 3. 0% Qinyu San group was significantly higher than that of the 0% group. Conclusion:Qinyu San powder might be an strategy for controlling chicken colibacillosis.%目的：探讨芩榆散对鸡人工感染大肠杆菌病的治疗效果。方法：选取200羽14日龄罗曼公鸡，其中40只为空白对照组，治疗试验选取160羽接种大肠杆菌O1造病，次日将发病鸡随机分为4组，其中第1-3组分别为高、中、低剂量的药物治疗试验组，分别在饲料中添加3.0％、1.5％和0.75％的芩榆散，第4组为阳性对照组，不用药，第5组为空白对照组，各组连续处理5 d，第6 d统计各组的有效率。结果：高剂量组芩榆散的痊愈率（67.5％）和有效率（85％）最高，均显著高于阳性对照组。结论：该散剂可用于鸡大肠杆菌病的治疗。
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