目的：：探讨脑电图和功能磁共振成像( EEG-fMRI)同步联合技术在颞叶癫痫致痫灶时间和空间定位中的应用价值。方法：17例有病灶性的颞叶癫痫患者,手术前均接受EEG-fMRI检查,手术中采用皮层电极和深部电极描记,确定致痫灶的真实位置和范围,并与EEG-fMRI方法所确定的致痫灶位置和范围进行比较。结果：7例二者所确定的致痫灶位置和范围完全相同,10例所确定的致痫灶中心位置相同,但其中9例同步EEG-fMRI范围较大,1例皮层电极和深层电极范围较大。结论：EEG-fMRI是一种无创的结合时间和空间信息的定位方法,可以在fMRI影像上直观了解致痫灶的位置和范围。%Objective:To investigate the application of the synchronization imaging of electroencephalogram-functional MRI ( EEG-fMRI) in the locating the epilepsy lesion of temporal lobe. Methods:Seventeen patients with temporal lobe epilepsy were detected using EEG-fMRI. The true location of epileptogenic focus and scope was identified by cortical electrode and deep electrode, which was compared with the results of EEG-fMRI. Results:The location and scope of disease detected by two methods were exactly same in 7 cases. The centre of lesions in 10 cases were unanimous,but the concordant scope was big. Conclusions:EEG-fMRI is a noninvasive method to locate the time and space,which can intuitively know the location of epileptogenic focus and scope in fMRI imaging.
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