Systems biology is an integrative discipline of biosystems research by methodology of systems theory and experimental, computational and engineering biology. Systems genetics is investigated in the fields of genomic stability and evolution, functional genomics and complexity of traits etc. Synthetic biology, the applied systems biology in engineering of artificial biosystems, is as the systems biotechnology of genetic engineering, computer aid design of cell molecular systems and synthesis of artificial genomic structures. The structural theory of systems and synthetic biology, technology of sequence tagged fragments display and micro-fluidic biochips, was dis cussed in the exploring of molecular biosystems at the aspects of cellular metabolism, reproduction and self-organization of genomes and morphogenesis of organism.%系统生物学是系统理论和实验生物技术、计算机数学模型等方法整合的生物系统研究,系统遗传学研究基因组的稳态与进化、功能基因组和生物性状等复杂系统的结构、动态与发生演变等.合成生物学是系统生物学的工程应用,采用工程学方法、基因工程和计算机辅助设计等研究人工生物系统的生物技术.系统与合成生物学的结构理论,序列标志片段显示分析与微流控生物芯片,广泛用于研究细胞代谢、繁殖和应激的自组织进化、生物体形态发生等细胞分子生物系统原理等.
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