总结了髓样抑制细胞(MDSC)在促进炎症发生和肿瘤细胞的免疫逃逸中发挥的作用,以及促进肿瘤发生发展的作用机制。可为以后探讨肝纤维化和肝癌发病的免疫学机制提供一条新的思路,也将有利于未来寻找肝纤维化和肝癌治疗的有效靶点。%The role of myeloid-derived suppressor cells (MDSCs)in promoting inflammatory response and immune escape of tumor cells and the mechanism by which MDSCs promote the development and progression of tumors are reviewed.This could provide a new way for the investigation of immunological mechanism of liver fibrosis and liver cancer.Besides,MDSCs may be an effective therapeutic target for liver cirrhosis and liver cancer.
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