Objective To explore the clinical efficacy of transrectal lapse valve repair in the treatment of patients with middle and low rectovaginal fistula.Methods Totally 24 patients with middle and low rectovaginal fistula were divided into transanal group (n =15) and transvaginal group (n =9).The transanal group was treated by rectal lapse valve repair,and the transvaginal group was treated with the transvaginal repair.The indexes of oxidative stress such as serum IL-6,ROS,CRP were compared between the two groups,and the success,recurrence and satisfaction rate were compared as well.Results After treatment,the levels of IL-6,ROS and CRP in both groups were significantly higher than those before treatment,but there were no significant differences in the stress response indexes between the two groups (P ＞ 0.05).The success rate and satisfaction rate in the transanal group were significantly higher than those in the transvaginal group (P ＜ 0.05),and the recurrence rate was significantly lower than the transvaginal group (P ＜ 0.05).Conclusion Transrectal lapse valve repair has higher success rate and low recurrence rate in the treatment of patients with middle and low rectovaginal fistula.%目的 探讨直肠推移瓣修补术治疗中低位直肠阴道瘘的临床疗效.方法 选取24例中低位直肠阴道瘘患者,分为经肛门组15例和经阴道组9例.经肛门组患者采用直肠推移瓣修补术治疗,经阴道组患者采用经阴道修补术治疗,比较2组患者血清各氧化应激指标白介素-6(IL-6)、活性氧类物质(ROS)、C反应蛋白(CRP)的水平.比较2组的成功率、复发率、满意率.结果 手术后,2组的IL-6、ROS、CRP水平均显著高于手术前,手术后2组的各应激反应指标水平无显著差异(P＞0.05).经肛门组患者的成功率和满意度显著高于经阴道组,复发率显著低于经阴道组(P＜0.05).结论 直肠推移瓣修补术治疗中低位直肠阴道瘘的成功率更高,且复发率低.
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