目的：对难治性肺炎及肺炎吸收缓慢患者应用纤支镜联合支气管肺泡灌洗治疗的效果及其不良反应情况进行分析探讨。方法选择2012年2月~2015年2月期间在我院接受治疗的128例难治性肺炎及肺炎缓慢吸收患者，使用随机数字表法将其分成观察组64例和对照组64例。对照组患者应用常规疗法予以治疗，观察组患者在其基础之上加用纤支镜联合支气管肺泡灌洗予以治疗。观察、比较两组患者的临床治疗效果、不良反应情况、血气分析指标以及CRP、IL-6的变化情况。结果经过相应的治疗之后，观察组患者治疗的总有效率为90．6%，明显高于对照组的70．3%(P<0．05)；在血气分析指标以及CRP、IL-6水平方面，两组患者都较治疗前显著改善(P<0．05)，并且观察组患者改善更加明显(P<0．05)；两组患者都没有出现严重的不良反应。结论难治性肺炎及肺炎吸收缓慢患者应用纤支镜联合支气管肺泡灌洗治疗，疗效显著，安全性高，具有肯定的临床应用价值。%Objective To analyze and discuss the curative effect and adverse reactions of bronchoalveolar lavage in the treatment of patients with refractory pneumonia. Methods 128 patients with refractory pneumonia and pneumonia absorbed slowly were selected from February 2012 to February 2015, and they were randomly divided into the observation group (64 cases) and the control group (64 cases). The control group was treated with conventional therapy, and the observation group was additionally given bronchoalveolar lavage. The clinical outcomes, adverse re-actions, blood gas analysis and changes in IL-6 and CRP were observed and compared between the two groups. Re-sults After the treatment, the total efficiency of the observation was 90. 6%, which was significantly higher than that of the control group (70. 3%) (P<0. 05). Blood gas analysis, IL-6 and CRP all improved significantly after the treatment (P<0. 05), and the improvement was more pronounced in the observation group than in the control group (P<0. 05). There was no serious adverse reactions occurred in the two groups. Conclusion Bronchoalveolar lav-age has significant curative effect and high safety in the treatment of patients with refractory pneumonia.
展开▼
