目的：探讨胰岛素泵治疗肺结核合并糖尿病患者的临床效果。方法将初治菌阳空洞性肺结核合并2型糖尿病患者随机分为持续皮下胰岛素输注组（CSII组）、多次皮下胰岛素注射组（MSII组）、口服降糖药物治疗组（OAD组），比较观察三组患者治疗前及治疗2个月后血糖控制情况、痰菌转阴率、病灶吸收有效率、空洞闭合率等方面的差异。结果 CSII组、MSII组在血糖控制、痰菌转阴率、病灶吸收有效率、空洞闭合率均显著高于OAD组，CSII组胰岛素用量、血糖达标时间显著优于MSII组。结论胰岛素泵治疗肺结核合并糖尿病，在平稳有效安全降糖的同时更有利于促进痰菌转阴。%Objective To investigate the clinical efficacy of insulin pump in the treatment of diabetic pa-tients complicated with pulmonary tuberculosis.Methods The initial treatment of bacillary cavitary pulmonary tu-berculosis patients complicated with type 2 diabetes were randomly divided into the continuous subcutaneous insulin infusion group (the CSII group),the multiple subcutaneous insulin injection group (the MSII group),and the oral hypoglycemic drug treatment group (the OAD group).Their glycemic control,sputum negative conversion,lesions absorption and cavity closure rate were compared among the three groups before and 2 months after the treatment.Re-sults The glycemic control,sputum negative conversion,lesions absorption and cavity closure rate blood glucose were significantly better in the CSII group and the MSII group than in the OAD group,and the usage of insulin and the time of blood sugar back to normal were better in the CSII group than in the MSII group.Conclusion CSII can achieve stable and effective glucose control and promote negative sputum in the treatment of pulmonary tuberculosis patients complicated with type 2 diabetes mellitus.
展开▼
