目的 系统评价中西医结合治疗咳嗽变异性哮喘的疗效.方法 计算机检索MEDLINE( Ovid,1950-2011年)、PubMed(1992-2011年)、EMBASE(1966-2011年)、Cochrane图书馆(2011年第2期)、中国生物医学文献数据库(SinoMed 1978年至2011年2月)、万方数据全文(1998-2011年)、维普医药信息资源系统(VIP1989-2011年)、中国数字图书馆(1994-2011年)等数据库,结合手工检索相关杂志；按系统评价方法筛选试验、评价质量、提取资料,并用WinBUGS软件进行贝叶斯Meta分析.结果 共纳入28个试验,含2 226例患者；纳入试验的方法学质量均低下.贝叶斯Meta分析显示,试验组相对于对照组提高一个或一个以上更佳疗效的比数比为2.936[95％可信区间(2.454,3.508)].结论 虽然中西医结合治疗咳嗽变异性哮喘有益,但由于纳入试验的研究方法学质量低下,需要进一步高质量随机对照研究加以证实.%Objective To evaluate the effect of integrated Chinese-western therapy for cough variant asthma (CVA). Methods The Cochrane Library(Issue 2, 2011), The MEDLINE(Ovid, 1950-2011), PubMed( 1992-2011), EMBASE (1966-2011), SinoMed (1978.01 to 2011.02), WANFANG database (1998-2011), VIP(1989-2011), CHKD( 1994-2011) were searched, and relevant journals were searched by manual retrieval. Studies were selected and data were collected and the quality of included studies was assessed according to the principles of systematic reviews. Bayesian meta-analysis was performed using WinBUGS. Results 28 trials including 2 226 patients were identified. All of the trials were not adequate in methodological quality. Meta-analysis showed that the OR of having a better response on the experimental treatment than on the control was 2.936 [95%CI(2.454,3.508)]. Conclusion The results showed that the patients with CVA were benefited from integrated Chinese-western therapy, but more clinical trials of high methodological quality are needed to confirm this conclusion due to low quality of trials.
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机译：贝叶斯统计方法，Brian J.Reich Sujit K. Ghosh，Boca Raton，FL：Chapman和Hall / CRC，2019，硬覆盖。 PP。288.9.96美元。 贝叶斯统计方法贝叶斯统计方法，Brian J.Reich Brian J. Brian J.Reich Reich Sujit K. Ghosh Sujit K. Sujit K. Ghosh Ghosh，Boca Raton，Fl Boca Raton，FL：Chapman和Hall / CRC Chapman和Hall / CRC，2019 2019，硬封面。 PP。288.9.96美元。
