目的：研究精神分裂症患者书写特征与治疗效果的相关性，探讨具有攻击行为对患者书写特征的影响。方法收集精神分裂症患者在入院时，治疗1周、2周、4周、8周的随意书写和固定摘抄，并进行阳性和阴性症状量表（PositiveandNegativeSyndromeScale，PANSS）及修订版外显攻击行为量表（ModifiedOvertAggressionScale，MOAS）评分。选取“字体与格线关系”、“有无大笔画”两项书写特征进行治疗前后比较。结果精神分裂症患者治疗8周后PANSS得分下降，病情好转，书写特征有改善；有攻击行为的患者书写特征在治疗前后差异有统计学意义（P<0.05）。结论精神分裂症患者的书写特征变化与治疗效果具有相关性，有攻击行为的精神分裂症患者书写特征异常变化在治疗后有改善。%Objective To explore the relevance between writing characteristic and therapeutic effect in schizophrenia and to discuss the influence of aggressive behavior on writing characteristic. Methods Re-coding the casual and fixed writing in admission, one week, two weeks, four weeks, eight weeks after treatment and rating Positive and Negative Syndrome Scale (PANSS) and Modified Overt Aggression Scale (MOAS). Choosing two characteristics, “relationship between font and grid lines” and “having big strokes or not”, and comparing before and after treatment. Results Eight weeks after treatment, the score of PANSS decreased. The condition of patients and the writing characteristic improved as well. The differ-ences of writing characteristics were statistically significant in patients with aggressive behavior before and after treatment (P<0.05). Conclusion The writing characteristic has relation with therapeutic effects and improved with therapeutic effects in aggressive patients.
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