Genetic Polymorphism of Nine Non-CODIS STR Loci in Hu-nan Province-based Chinese Han Population

GUO Juan-juan; LIU Ying; GUO Ya-dong; YAN Jie; CHANG Yun-feng; CAI Ji-feng; LU Ting; ZHA Lagabaiyila

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Genetic Polymorphism of Nine Non-CODIS STR Loci in Hu-nan Province-based Chinese Han Population

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Objective To determine the allelic frequency distribution and genetic parameters of nine non-CODIS DNA index systems of the short tandemrepeat (STR ) loci (D2S1772, D6S1043, D7S3048, D8S1132, D11S2368, D12S391, D13S325, D18S1364, and GATA198B05). Methods A total of 353 blood samples were collected, extracted, amplified, and analyzed fromunrelated healthy individuals of Han na-tionality in Hunan Province, China. Results O ne hundred and fourteen alleles were observed in the pop-ulation with corresponding allelic frequencies ranged from0.001 0 to 0.323 0. For all the nine non-CODIS STR loci, the observed genotypic data showed no significant deviations fromthe Hardy-W einberg equi-librium. The Ho, He, PIC, D P, and PE of the studied non-CODIS STR loci ranged from0.108 0 to 0.195 0, 0.805 0 to 0.892 0, 0.770 0 to 0.860 0, 0.925 0 to 0.966 0 and 0.607 0 to 0.780 0, respectively. Conclusion N ine non-CODIS STR loci have high degrees of polymorphisms, which may be useful in in-dividual forensic identification and parentage testing in forensic practice.

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来源
《法医学杂志》 |2014年第6期|441-445|共5页
作者
GUO Juan-juan; LIU Ying; GUO Ya-dong; YAN Jie; CHANG Yun-feng; CAI Ji-feng; LU Ting; ZHA Lagabaiyila;
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作者单位

Department of Forensic Medicine;

School of Basic Medicine;

Central South University;

Changsha 410013;

China;

Department of 0ral and Maxillofacial Surgery;

Xiangya Stomatological Hospital;

Central South University;

Changsha 410013;

China;

Department of Forensic Medicine;

School of Basic Medicine;

Central South University;

Changsha 410013;

China;

Department of Forensic Medicine;

School of Basic Medicine;

Central South University;

Changsha 410013;

China;

Department of Forensic Medicine;

School of Basic Medicine;

Central South University;

Changsha 410013;

China;

Department of Forensic Medicine;

School of Basic Medicine;

Central South University;

Changsha 410013;

China;

Department of Forensic Medicine;

School of Basic Medicine;

Central South University;

Changsha 410013;

China;

Department of Forensic Medicine;

School of Basic Medicine;

Central South University;

Changsha 410013;

China;

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正文语种 eng
中图分类法医物证检验学;
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Genetic Polymorphism of Nine Non-CODIS STR Loci in Hu-nan Province-based Chinese Han Population

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