首页> 中文期刊> 《福建医科大学学报》 >福建省艾滋病抗病毒治疗患者生存时间影响因素分析

福建省艾滋病抗病毒治疗患者生存时间影响因素分析

         

摘要

Objective To explore the influential factors of aids patients' survival time after antiretroviral treatment, provide references for further improving the living conditions of patients and the quality of future antiretroviral treatment. Methods The data of antiretroviral therapy in Fujian province was collected by the information system for AIDS control and prevention developed by China CDC, and was analyzed by using SPSS15. 0. A total of 1 061 patients were selected according to the standard, 66 patients (6. 22%) had died of AIDS-related illnesses. Results Cox proportional hazards model analysis identified several factors related with survival time including less than 200 of baseline CD4 T lymphocyte count, and continuous or intermittent fever at the baseline. Conclusions Considering the factors related with the survival of the patients after HAART, providing timely treatment once the requirement is fulfilled would improve the survival and prognosis of patients.%目的 了解福建省艾滋病病毒(HIV)感染者/艾滋病(AIDS)患者接受抗病毒治疗后生存时间的影响因素,为进一步改善患者的生存状况,提高抗病毒治疗工作质量提供参考依据.方法 利用国家统一的中国疾病预防控制系统艾滋病综合防治信息系统中福建省治疗数据信息,使用SPSS 15.0进行相关分析.通过筛选,本次研究共纳入1 061例患者,死于AIDS相关疾病66例(6.22%).结果 Cox比例风险模型分析结果 表明,基线CD4+T淋巴细胞计数<200、基线时患者有持续或间断发热影响患者抗病毒治疗后生存时间.结论 结合抗病毒治疗生存时间影响因素分析,在疾病早期符合抗病毒治疗标准时尽早开始治疗对患者生存预后有益.

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