Background There are limited data on long-term (＞ 5 years) outcomes of drug-eluting stent (DES) implantation compared with coronary artery bypass grafting (CABG) for ostial/midshaft left main coronary artery (LMCA) lesions.Methods Of the 259 consecutive patients in Beijing Anzhen Hospital with ostial/midshaft LMCA lesions,149 were treated with percutaneous coronary intervention (PCI) with DES and 110 were with CABG.The endpoints of the study were death,repeat revascularization,myocardial infarction (MI),stroke,the composite of cardiac death,and major adverse cardiac and cerebrovascular events (MACCE,the composite of cardiac death,MI,stroke or repeat revascularization).The duration of follow-up is 7.1 years (interquartile range 5.3 to 8.2 years).Results There is no significant difference between the PCI and CABG group during the median follow-up of 7.1 years (interquartile range:5.3-8.2 years) in the occurrence of death (HR:0.727,95％ CI:0.335-1.578;P =0.421),the composite endpoint of cardiac death,MI or stroke (HR:0.730,95％ CI:0.375-1.421;P =0.354),MACCE (HR:1.066,95％ CI:0.648-1.753;P =0.801),MI (HR:1.112,95％ CI:0.414-2.987;P =0.833),stroke (HR:1.875,95％ CI:0.528--6.659;P =0.331),and repeat revascularization (HR:1.590,95％ CI:0.800-3.161;P =0.186).These results remained after multivariable adjusting.Conclusion During a follow-up up to 8.2 years,we found that DES implantation had similar endpoint outcomes compared with CABG.
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机译：New Predictors of Early and Late Outcomes after Primary Percutaneous Coronary Intervention in Patients with ST-Segment Elevation Myocardial Infarction and Unprotected Left Main Coronary Artery Culprit Lesion
机译：Four-year outcomes after percutaneous coronary intervention of unprotected left main coronary artery disease in patients with stable angina and acute coronary syndrome
机译：aneurisma em ponte de veia safenaparaartériacoronáriamargininalesquerda，roto paraobrônquiodosdoaneurysm in the hyhenhen vein bypass suruplant to left marginal coronary artery，brokeed up to left bronchus
