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《海南医科大学学报（英文版）》
>Effect of Hemabate combined with packing therapy on the systemic stress response in patients with postpartum hemorrhage after placenta previa cesarean section
Effect of Hemabate combined with packing therapy on the systemic stress response in patients with postpartum hemorrhage after placenta previa cesarean section
Objective:To discuss the effect of Hemabate combined with packing therapy on the systemic stress response in patients with postpartum hemorrhage after placenta previa cesarean section. Methods:70 patients with postpartum hemorrhage after placenta previa cesarean section who were treated in Chengdu Women & Children's Central Hospital between January 2014 and February 2017 were collected and then divided into the control group (n=35) who received uterine packing therapy and the observation group (n=35) who received Hemabate combined with packing therapy according to random number table. Serum levels of oxidative stress indexes and stress hormones immediately after operation and 24 h after operation were compared between two groups of patients.Results: Immediately after operation and 24 h after operation, serum oxidative stress indexes ROS and MDA levels of observation group were significantly lower than those of control group while SOD, GSH-px and CAT levels were significantly higher than those of control group, and serum stress hormones NE, E and Cor levels were significantly lower than those of control group.Conclusion: Hemabate combined with packing therapy can effectively reduce systemic stress response in patients with postpartum hemorrhage after placenta previa cesarean section, is a more ideal way of the bleeding.
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Department of Obstetrics and Gynecology, Chengdu Women & Children's Central Hospital in Sichuan Province, Chengdu City, Sichuan Province, 610091, China;
