目的 探讨不同程度单纯三尖瓣反流胎儿脐动脉(umbilical artery,UA)及静脉导管(ductus venous,DV)血流频谱参数变化及临床价值.方法 选取孕20～41+6周孕妇253例(除外心内及心外畸形),根据三尖瓣反流程度不同分为:轻度反流组68例,中度反流组20例,无三尖瓣反流胎儿165例为对照组.获取各组UA和DV血流频谱.测量胎儿UA血流频谱参数:收缩期峰值流速,舒张末期流速,计算收缩期峰值流速与舒张末期流速比值(peak systolic velocity/end diastolic velocity,S/D)、阻力指数(resistence index,RI)、搏动指数(pulsatility index,PI).测量DV血流频谱参数:心室收缩期峰值流速,心室舒张期峰值流速,心房收缩期峰值流速,计算心室收缩期峰值流速与心房收缩期峰值流速比值(peak ventricular systolic velocity/peak atrial systolic velocity,S/A)、RI及PI.对比各组胎儿上述参数.结果 轻度反流组UA血流频谱参数S/D、RI及PI和DV血流频谱参数S/A、RI及PI与对照组差异均无统计学意义(P>0.05),中度反流组UA血流频谱参数S/D、RI及PI和DV血流频谱参数S/A、RI、PI均较对照组及轻度反流组增高,差异均有统计学意(P0. 05). The parameters of UA blood flow spectrum S/D, RI, PI and DV in moderate reflux group were higher than those in control group and mild reflux group (P<0. 05). Conclusion UA and DV blood flow spectrum can be used to evaluate the condition of fetus and placenta when tricuspid regurgitation happens. Therefore, it can provide substantial support for intervening measures.
展开▼
