Engineering thermodynamic is used to deduce the calculating equation of air resistance in mine ventilation．Some factors that affect the accuracy of air resistance such as the change of interal energe of air，compression of air and heat exchange between air flow and mine are discussed．It is more perfect in theory，all parameters in the equation can be measured easily．Compraing with the conventional Bemoulli equation，the thermodynamic calculation is more correspondent to the reality．%应用工程热力学理论推导出矿井通风阻力的热力学计算公式，该公式比较全面地反映了空气内能的变化、空气的可压缩性及风流与矿井进行的热量交换等对阻力计算精度的影响，理论上更加完善．该公式中所有的参量均易测定，比应用传统的伯努利方程计算通风阻力更符合工程实际．
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