Objective:To explore the relationship between levels of C-reactive protein,Serum Uric Acid,Fibrinogen and the extent and Severity of artery disease inpremenopausal and postmenopausal women with coronary disease. Methods:80women diagnosed as coronary disease by coronary angiography were enrolled. According to coronary angiography,which was divided into two groups:pre-menopausal group(40cases)and,postmenopausal group(40cases),which was further divided into three subgroups:single vessel disease group,double vessels disease group and multi-vessels disease group. The level of CRP、SUA and FIB were measured, and to analyze the relation Between Levels of C-reactive protein,Serum Uric Acid,Fibrinogen and the Severity of coronary artery. Results:The levels of CRP、SUA and Fg positively related with the Severity of coronary artery. Conclusion:The level of CRP、UA and FIB maybe were independent risk factors for the Severity of coronary artery.%目的：：比较分析女性冠心病病人的冠脉病变特点及其与C-反应蛋白( CRP)、尿酸( UA)、纤维蛋白原( FIB)的相关性。方法：选取经冠脉造影确诊为冠心病( CHD)的女性80例，其中绝经前40例，绝经后40例，根据冠脉造影病变受累情况分为单支病变组、双支病变组、多支病变组，通过对血清中CRP、UA、FIB水平的检测，探索其与冠脉病变程度的是否存在相关性。结果：女性CHD病人血清中CRP、UA、FIB水平随冠脉病变程度的加重呈逐渐升高趋势。结论：女性CHD血CRP、尿酸、纤维蛋白原水平的升高与冠状动脉严重程度具有相关性。
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