Alternatives for large-scale production of cultured beef:A review

Matilda S M Moritz; Sanne E L Verbruggen; Mark J Post

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Alternatives for large-scale production of cultured beef:A review

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Cultured beef is a method where stem cel s from skeletal muscle of cows are cultured in vitro to gain edible muscle tissue. For large-scale production of cultured beef, the culture technique needs to become more efifcient than today’s 2-dimensional (2D) standard technique that was used to make the ifrst cultured hamburger. Options for efifcient large-scale production of stem cel s are to culture cel s on microcarriers, either in suspension or in a packed bed bioreactor, or to culture aggregated cel s in suspension. We discuss the pros and cons of these systems as wel as the possibilities to use the systems for tissue culture. Either of the production systems needs to be optimized to achieve an efifcient production of cultured beef. It is anticipated that the optimization of large-scale cel culture as performed for other stem cel s can be translated into successful protocols for bovine satel ite cel s resulting in resource and cost efifcient cultured beef.

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《农业科学学报（英文版）》 |2015年第2期|208-216|共9页
作者
Matilda S M Moritz; Sanne E L Verbruggen; Mark J Post;
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Department of Physiology, Maastricht University, Maastricht 6229 ER, The Netherlands;

Department of Physiology, Maastricht University, Maastricht 6229 ER, The Netherlands;

Department of Physiology, Maastricht University, Maastricht 6229 ER, The Netherlands;

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Alternatives for large-scale production of cultured beef:A review

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