Women’s preconception health patterns in traditional Chinese medicine as a predictor of fertility outcomes

Xia-qiu Wu; Wendy Satmary; Jin Peng; Ka-kit Hui

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Women’s preconception health patterns in traditional Chinese medicine as a predictor of fertility outcomes

机译：妇女在中医中的先注健康模式作为生育结果的预测因素

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Objective: To examine the association between traditional Chinese medicine(TCM), preconception health patterns and fertility outcomes.Methods: A community-based prospective cohort study was conducted in China. A total of 3012 newly married women who were willing to conceive within 2 years were enrolled in the study and took National Free Prepregnancy Checkups(NFPC). A reliably structured self-rating scale was used to measure the TCM preconception health patterns of the enrolled women. A 3-year follow-up was conducted to obtain the fertility outcomes, including pregnancy rate, time to pregnancy, spontaneous miscarriage and newborn status. Statistical analyses were conducted using Chi-square or Fisher’s exact tests, logistic regression models, general linear models and the Cox proportional hazard model.Results: The fertility outcomes showed no statistic correlations to the terms of NFPC in this population.Approximately a half of the women(46.66%) had unhealthy patterns. Women with qi & blood-deficiency(odds ratio [OR] = 35.19, 95% confidence interval [CI] = 1.55–801.15) or qi-stagnation(OR = 4.55, 95% CI =0.90–23.06) pattern took a longer time to get pregnant, and those with qi-stagnation(OR = 2.05, 95% CI =1.1–3.82) or yang-deficiency(OR = 1.91, 95% CI = 1.12–3.25) pattern had a higher risk of spontaneous miscarriage.Conclusion: Three unhealthy TCM patterns during the preconception period might be risk factors for low fecundity or poor pregnancy outcomes. The TCM preconception pattern identification may provide a convenient and effective way to screen for potential pregnancy risks beyond the NFPC. Further, appropriate interventions based on the TCM preconception health patterns are needed to improve quality in women’s fecundability and birth outcomes.

机译：目的：探讨中医（中医），先入为主模式与生育效果的关联。方法：在中国进行了一项社区的未来队列研究。共有3012名愿意在2年内进行设想的新婚妇女在研究中注册，并采取了国家自由妊娠检查（NFPC）。可靠的结构性自评估量表用于衡量登记妇女的中医偏见健康模式。进行了3年的随访，以获得生育结果，包括怀孕率，怀孕时间，自发流产和新生儿。使用Chi-Square或Fisher的精确测试，Logistic回归模型，一般线性模型和Cox比例危险模型进行统计分析。结果：生育结果显示出与本人NFPC的条款没有统计学相关性。超过一半女性（46.66％）有不健康的模式。血清缺乏的妇女（缺乏赔率[或] = 35.19,95％置信区间[CI] = 1.55-801.15）或qi-stagnation（或= 4.55,95％ci = 0.90-23.06）模式花了更长的时间为了怀孕，Qi-stagnation（或= 2.05,95％ci = 1.1-3.82）或阳虚（或= 1.91,95％ci = 1.12-3.25）模式具有更高的自发流产的风险。结论：在偏见期间的三种不健康的中医模式可能是低繁殖或怀孕结果差的危险因素。 TCM偏心模式识别可以提供一种方便且有效的方法来筛选出于NFPC之外的潜在妊娠风险。此外，需要基于TCM先入型健康模式的适当干预，以提高女性兴奋性和出生结果的质量。

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《结合医学学报：英文版》 |2020年第003期|P.222-228|共7页
作者
Xia-qiu Wu; Wendy Satmary; Jin Peng; Ka-kit Hui;
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作者单位

School of Basic Medical Sciences Zhejiang Chinese Medical University Hangzhou 310053 Zhejiang Province ChinaCenter for East-West Medicine David Geffen School of Medicine University of California Los Angeles CA 90024 USA;

Department of Obstetrics&Gynecology David Geffen School of Medicine University of California Los Angeles CA 90024 USA;

Institute of Basic Research in Clinical Medicine China Academy of Chinese Medical Sciences Beijing 100700 China;

Center for East-West Medicine David Geffen School of Medicine University of California Los Angeles CA 90024 USA;

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收录信息中国科学引文数据库(CSCD);
原文格式 PDF
正文语种 chi
中图分类中医妇产科;
关键词
Preconception care; Fertility; Traditional Chinese medicine; Women’s health; Risk assessment;

机译：先入为主;生育;中医;妇女的健康;风险评估;

Women’s preconception health patterns in traditional Chinese medicine as a predictor of fertility outcomes

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