Bacillus amyloliquefaciens is a strain similar to B. subtilis,a beneficial microbe that can produce spore, Gram-positive,and possessing biocontrolling activity. During its metabolism it produces antibiotic substance,a varie-ty of antibiotic preparations or antibiotic extracts with broad antibiotic spectrum,non toxic,non harms,non residues, long effectiveness for a given period of time,and other advantages. It can be widely applied in keeping fruits and vegetables fresh,and in biocontrolling microbial pests during their growth and post-harvest. It is a very ideal biocon-trolling microbe with the most developing value. In this paper the studies,the current application of B. amyloliquefa-ciens were drawn and summarized from aspect of the antibiotic mechanism,the antibiotic gene component,the estab-lishment of genetic engineering strain,the development of resistance products,the controlling against microbial pests,and other aspects,and accordingly to provide references for its large-scale safety application in agricultural bio-engineering.%解淀粉芽胞杆菌（Bacillus amyloliquefaciens）是与枯草芽胞杆菌相似，可产芽胞、革兰阳性（G +）、具有生防活性的益生细菌。其代谢过程中产生的抗菌物质种类多、抗菌谱广，其抗菌制剂或抗菌提取物具有无毒、无害、无残留、抑菌时效长等优点，可广泛应用于果蔬保鲜、果蔬生长期及采后微生物病害的生物防治，是极具开发价值的生防菌。本文从抗菌机理、抗性基因组成、基因工程菌构建、抗性产品开发及对微生物病害防治等几个方面，对解淀粉芽胞杆菌的研究及应用现状进行了归纳和总结，为其在农业生物工程中的规模化安全应用提供参考。
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