目的:探索胎盘部位滋养叶细胞肿瘤(placental site trophoblastic tumor,PSTT)的临床病理特征.方法:对1例PSTT进行大体、组织病理学和免疫组化染色观察,并复习相关文献.结果:患者年龄39岁,症状主要为停经后出血.镜下瘤细胞呈单个、条索状或片状浸润于肌纤维间.结论:PSTT发生于着床部位的中间型滋养细胞,多见于官腔,发生于输卵管者罕见.免疫组织化学特征性表达可辅助诊断和鉴别诊断.%Objective: To investigate the clinical and pathological features of placental site trophoblastic tumor ( PSTT) . Methods: The clinical data was retrospectively analyzed for one case of PSTT. Histopathological and immu-nohistochemical changes of the tumor were also observed in the paraffin - embedded tissue samples. Results: A case of 39 - year - old female presented with vaginal bleeding after manolipsis. PSTT cells permeated between the myometrial fibers and vessels either individually or connecting in cords or sheets in a manner reminiscent of the implantation site reaction. Conclusion: PSTT is a tumor of implantation siteintermediate trophoblasts. The different pathologic features and immunophenotype are closely related with the difference in tumor cell differentiation.
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