Objective To explore the relationship between children's precocious puberty and environmental endocrine interferon ( EEDs) .Methods 63 cases of girls with precocious puberty in our hospital from April 2013 and March 2015 were selected as the ob-servation group, and 63 cases of healthy girls were selected as control group.The levels of serum EEDs and serum estradiol, ovarian volume, and uterine volume of both groups were detected and compared.Results The levels of DEHP, Op, BPA EEDs of the obser-vation were significantly higher than those of the control group, the difference between the two groups has statistical significance ( P <0.01);The ovarian volume, uterine volume, and estradiol level of the observation group were also significantly higher than those of the control group, the difference is statistically significant ( P <0.01).Conclusion EEDs and the onset of precocious puberty were closely related, which maybe the main cause of precocious puberty.%目的：探讨儿童性早熟与环境内分泌干扰素（ EEDs）的相关性。方法选择我院2013年4月至2015年3月收治的63例性早熟女童为观察组，另选健康女童63例为对照组，检测两组血清EEDs水平及卵巢体积、子宫体积、血清雌二醇水平等，进行对比分析。结果观察组DEHP、OP、BPA等EEDs指标水平明显高于对照组，两组差异有统计学意义（ P ＜0.01）；观察组卵巢体积、子宫体积、雌二醇等指标水平显著较对照组高，差异有统计学意义（ P ＜0．01）。结论 EEDs与性早熟发病呈密切相关性，可能是导致儿童性早熟的主要原因。
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