Objective To explore the spatial aggregation areas of hepatitis B infection in Nan-chang between 2005 and 2012,and to provide the idea and evidence for the prevention and control of hepatitis B in Nanchang.Methods Data of epidemic situation of hepatitis B in Nanchang be-tween 2005 and 2012 were analyzed using SaTScan software.Spatial aggregation characteristics of hepatitis B infection were investigated through analyzing epidemic situation of hepatitis B and ad-ministrative division map of Nanchang.Results The distribution of Hepatitis B infection was not random in Nanchang,and there were obvious spatial aggregation areas.Between 2005 and 2012, Jinxian County became the first class aggregation areas,and Donghu District,Xihu District,Qing-shanhu District,Qingyunpu District and Xinjian County alternately became the second class ag-gregation areas.There were no spatial aggregation in Nanchang County,Wanli District and Anyi County.Conclusion Spatial clustering analysis combined with geographic visualization visually displays aggregation areas and changes of hepatitis B infection,and provides new idea and basis for prevention and control of hepatitis B infection.%目的：尝试探索南昌市2005-2012年乙肝发病可能存在的空间聚集区域，为南昌市乙肝防控工作提供思路和依据。方法应用 SaTScan软件分析南昌市2005-2012年乙肝疫情资料，结合南昌市行政区划地图，探索南昌市乙肝发病的空间聚集特征。结果南昌市乙肝发病在空间上不是随机分布的，存在明显的空间聚集区域。2005-2012年，进贤县均为一类聚集区；东湖区、西湖区、青山湖区、青云谱区及新建县等区县交替成为二类聚集区；南昌县、湾里区、安义县等区县未出现发病聚集现象。结论将空间聚集性分析和地理可视化相结合，可以形象直观地显示乙肝发病的聚集区和变动情况，为该病的防控提供新的思路和依据。
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