首页> 中文期刊> 《海军医学杂志》 >全胸腔镜下肺叶切除术在早期非小细胞肺癌治疗中的疗效及安全性

全胸腔镜下肺叶切除术在早期非小细胞肺癌治疗中的疗效及安全性

         

摘要

Objective To evaluate the clinical efficacy and safety of thoracoscopic lobectomy in the treatment of early non -small cell lung cancer .Methods One hundred and twenty cases of early non-small cell lung cancer admitted into Leshan Hospital from April 2013 to May 2016 were recruited as study subjects , and were equally divided into the observation group (n=60) and the control group (n=60), in accordance with different treatment methods .The patients in the observation group underwent thoracoscopic lobecto-my, while the patients in the control group received lobectomy via conventional thoracotomy .Blood loss during surgery , surgical time, duration of hospitalization , duration of chest tube drainage , lymph node dissection number and rate of postoperative complication were compared between the patients of the 2 groups.Results When compared with that of the control group , blood loss during surgery for the patients of the observation group was significantly reduced , surgical time and duration of hospitalization were obviously shortened .Statis-tical significance could be seen, when comparisons were made between the 2 groups(P<0.05).There was no statistical significance in the duration of chest tube drainage for the patients of the 2 groups(P>0.05).Statistical significance could neither be seen in total a-mount of chest tube drainage , the number of lymph node dissection , and the rate of perioperative mortality in the patients of the 2 groups (P>0.05).The rate of complication for the patients of the observation group was 3.33%, while that of the control group was 25.00%, and statistical significance could be seen , when comparisons were made between the 2 groups(P<0.05).Conclusion The application of thoracoscopic lobectomy in the treatment of non-small cell lung cancer could significantly improve surgical effect , hasten patient recovery and decrease rate of complication after surgery .For this reason , it was worth further clinical extension .%目的 评价应用全胸腔镜肺叶切除术早期非小细胞肺癌临床疗效及安全性.方法 选取2013年4月至2016年5月我院胸外科收治的早期非小细胞肺癌患者120例,按照治疗方法分为观察组(60例)与对照组(60例),观察组患者行全胸腔镜下肺叶切除术,对照组患者行常规开胸肺叶切除术,比较2组患者术中出血量、手术时间、住院时间、胸腔引流时间、淋巴结清扫数目及术后并发症发生情况.结果 与对照组比较,观察组患者的术中出血量明显降低,手术时间、住院时间显著缩短,差异均有统计学意义(P<0.05);2组胸腔引流时间差异无统计学意义(P>0.05);2组患者的总引流量、淋巴结清扫数目、围术期死亡率比较差异均无统计学意义(P>0.05);观察组并发症总发生率为3.33%,对照组并发症总发生率为25.00%,差异有统计学意义(P<0.05).结论 全胸腔镜下肺叶切除术应用于早期非小细胞肺癌患者的治疗,能够显著改善患者手术情况,有助于术后恢复,降低并发症,值得临床推广.

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