Objective To evaluate the effect of integrated intervention for patients with gestational diabetes mellitus (GDM) undergoing predelivery insulin pump intensive therapy on glycemic control and perinatal outcome. Methods Totally 64 patients with GDM undergoing insulin pump intensive therapy were randomly divided into integrated intervention (II) group and routine nursing (RN) group from June 2010 to June 2013. Integrated interventions included GDM diet and upper limbs activity by MOTO med viva2 adaptive ergometer, education of harm to pregnant women and neonates from GDM, advantages of pump therapy, pumps managing training, complication prevention. GDM salons were hold aperiodically, and the individual normative technical training were implemented whenever necessary. Treatment compliance, time for successful treatment, daily insulin dosage, maternal and neonatal complications were assessed. Results Treatment compliance was significantly better in group II than that in group RN ( P<0.05). Both the daily insulin dosage and the incidence of hypoglycemia were significantly less in group II than those in group RN ( P<0.05). Conclusion Through integrated intervention of insulin pump therapy, patients have better treatment compliance, while with less insulin dosage, and the hypoglycemia is prevented and controlled effectively.%目的：探讨妊娠期糖尿病（gestational diabetes mellitus，GDM）患者实施产前胰岛素泵短期强化综合干预对血糖控制和妊娠结局的影响。方法2010年6月-2013年6月符合研究标准的GDM产前胰岛素强化治疗的64例患者随机分成综合干预组和常规护理组各32例。常规护理组患者给予常规护理干预，包括饮食与运动指导，相关知识宣教，胰岛素泵治疗的优越性介绍，胰岛素泵安装与护理以及并发症的防范。综合干预组患者在常规护理干预的基础上，给予短期强化综合干预，包括按照应用上肢功率计运动，举办沙龙活动和实施胰岛素泵个体化技术培训。观察两组患者遵医行为，血糖控制情况，记录低血糖、酮症酸中毒和皮肤感染发生情况，以及妊娠高血压综合征、早产、巨大儿等妇科、儿科、产科并发症情况。结果综合干预组遵医行为显著优于常规护理组（P＜0.05），两组血糖达标时间差异无统计学意义，但综合干预组日均胰岛素用量显著低于常规护理组（P＜0.05）。综合干预组产妇低血糖症状发生率显著均低于常规护理组（P＜0.05），两组产妇妊娠高血压综合征、早产及胎儿窘迫等差异无统计学意义。两组新生儿并发症差异无统计学意义。结论 GDM产前胰岛素泵短期强化治疗综合干预显著增强患者的遵医行为，有助平稳控制产前高血糖，可减少胰岛素用量，有效控制产妇低血糖症状发生。
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