Chemically modified carbon-based electrodes for the determination of paracetamol in drugs and biological samples

Wafaa Boumya; Nawal Taoufik; Mounia Achak; Noureddine Barka

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Chemically modified carbon-based electrodes for the determination of paracetamol in drugs and biological samples

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Paracetamol is a non-steroidal, anti-inflammatory drug widely used in pharmaceutical applications for its sturdy, antipyretic and analgesic action. However, an overdose of paracetamol can cause fulminant hepatic necrosis and other toxic effects. Thus, the development of advantageous analytical tools to detect and determine paracetamol is required. Due to simplicity, higher sensitivity and selectivity as well as costefficiency, electrochemical sensors were fully investigated in last decades. This review describes the advancements made in the development of electrochemical sensors for the paracetamol detection and quantification in pharmaceutical and biological samples. The progress made in electrochemical sensors for the selective detection of paracetamol in the last 10 years was examined, with a special focus on highly innovative features introduced by nanotechnology. As the literature is rather extensive, we tried to simplify this work by summarizing and grouping electrochemical sensors according to the by which manner their substrates were chemically modified and the analytical performances obtained.

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《药物分析学报：英文版》 |2021年第2期|138-154|共17页
作者
Wafaa Boumya; Nawal Taoufik; Mounia Achak; Noureddine Barka;
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作者单位

Sultan Moulay Slimane University of Beni Mellal;

Research Group in Environmental Sciences and Applied Materials(SEMA);

FP Khouribga;

B.P.145;

25000;

Khouribga;

Morocco;

Chouaib Doukkali University;

Ecole Nationale des Sciences Appliquees;

Laboratoire des Sciences de l’Ingenieur pour l’Energie;

El Jadida;

Morocco;

Chemical&Biochemical Sciences;

Green Process Engineering;

CBS;

Mohammed VI Polytechnic University;

Ben Guerir;

Morocco;

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原文格式 PDF
正文语种 chi
中图分类自动化技术及设备;
关键词
Paracetamol; Electrochemical sensors; Modified electrodes; Pharmaceutical samples;

Chemically modified carbon-based electrodes for the determination of paracetamol in drugs and biological samples

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