目的:评价锥形束CT(CBCT)测量绝经后骨质疏松症(PMO)患者下颌骨的骨密度(BMD)的可行性.方法:随机抽样选择45例绝经后妇女作为研究对象,使用双能X线吸收法(DXA)测量研究对象的腰椎BMD进行分组(PMO组,T≤-2.5;健康对照组,T≥-1.0).同时使用DXA测量下颌骨BMD,使用CBCT测量腰椎和下颌骨BMD相关的指标CTI(S)、CTI(I)和CTMI,对比分析CBCT指标与BMD的相关性.结果:45例受试者26例诊断为PMO(BMD=0.623±0.056),19例为健康对照组(BMD=0.973±0.055),(P＜0.05;下颌骨BMD在PMO组和对照组分别为0.776±0.133和0.850 ±0.122,P＞0.05.在下颌骨的CBCT图像中PMO组CTI(S)、CTI(I)和CTMI均高于对照组(P＜0.05).以上参数与下颌骨BMD无相关性(P＞0.05),腰椎的CBCT各项参数与腰椎BMD呈正相关(P＜0.05).结论:应用CBCT测量PMO患者下颌骨BMD较DXA测量更具灵敏性.%Objective:To evlauate the mandibular bone mineral density(BMD) in postmenopausal osteoporotic(PMO) women by cone beam CT(CBCT) and to explore its clinical application.Methods:The BMD of the lumbar vertebrae and mandibular bone of 45 postmenopausal women was examined and calculated by dual energy X-ray absorptiometry(DXA) and CBCT respectively.The subjects were grouped by BMD value of lumbar vertebrae (PMO group,T ≤-2.5;healthy control group,T ≥-1.0).Correlation of CBCT indexes CTI (S),CTI(I) and CTMI with DXA index BMD was analyzed.Results:26 subjects were grouped into PMO (BMD =0.623 ± 0.056) and 19 into healthy control(BMD =0.973 ± 0.055)(P ＜ 0.05).The mandbular BMD in PMO and control groups was 0.776 ± 0.133 and 0.850 ± 0.122 (P ＞ 0.05) respectively.In PMO group all the CBCT indexes of mandibular bone were higher than those in the control group (P ＜ 0.05),no correlation was found between the CBCT indexes and BMD (P ＞ 0.05),while the CBCT indexes of the lumbar vertebrae were positively correlated with the BMD (P ＜ 0.05).Conclusion:CBCT is more sensitive than DXA in the assessment of mandibular BMD in PMO subiects.
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