How to explore the effects of sex hormone on blood vessels

Sun Mei-li; Nie Min; Liu Bing; Du Zhi-jun; Ge Qin-sheng

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How to explore the effects of sex hormone on blood vessels

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The risk of cardiovascular disease increases along with aging. There are increasing interests in researches on the protective effects of hormone replacement therapy (HRT)on cardiovascular system in postmenopausal women. In this article we will review how we have explored the evidence of different sex hormones on blood vessels since 1996. The results showed that low-dose HRT significantly protected cardiovascular system in postmenopausal women.However, the high-dose 17β-estradiol (E2), with or without progesterone (P) or testosterone (T), or any hormone alone, as their concentrations increase, may even inhibit the protective effects of low-dose HRT on blood vessels.

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《生殖医学杂志》 |2004年第z1期|75-78|共4页
作者
Sun Mei-li; Nie Min; Liu Bing; Du Zhi-jun; Ge Qin-sheng;
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作者单位

Peking Union Medical College Hospital,CAMS and PUMC,Bejing 100730, China;

Peking Union Medical College Hospital,CAMS and PUMC,Bejing 100730, China;

Peking Union Medical College Hospital,CAMS and PUMC,Bejing 100730, China;

Peking Union Medical College Hospital,CAMS and PUMC,Bejing 100730, China;

Peking Union Medical College Hospital,CAMS and PUMC,Bejing 100730, China;

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原文格式 PDF
正文语种 chi
中图分类卵巢疾病;
关键词
Hormone replacement therapy; 17β-estradiol; Progesterone; Testosterone; Tissue factor; Postmenopausal women;

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How to explore the effects of sex hormone on blood vessels

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