This paper attempts to build a theoretical framework from government-enterprise cooperative innovation to regional innovation, analyses the relationship between the government and enterprises evolving in the regional innovation, and finally conducts an empirical study based on Xinchang country, Zhejiang province.Research findings show that, according to the interactive relationship between the government and enterprises in the cooperative innovation, there are five stages in the regional innovation system evolution: initial phase, discrete phase, integrative phase, collaborative phase and synergetic phrase.In the innovation game between the local government and enterprises, the former focuses on whether the enterprises' innovation ability and innovation power can create greater social benefits for the region than what the government has invested, whereas the enterprises attach more importance to making correct innovative decisions based on government support, technology accumulation, capital power and other costs and benefits.The combination of the functional transition of the local government from "a housekeeper" to "a bartender" and the cumulative effect of input and output of enterprise innovation is the decisive factor for Xinchang's innovation drive path.As the regional innovation system develops from integrative phase to synergetic phase, leading enterprises have begun to build the global R&D center through multinational cooperation, mergers and acquisitions, forming an integrated innovative network by using domestic and foreign innovation resources.%通过构建一个从政企合作创新到区域创新系统的理论分析框架,并以此分析区域创新博弈中政企关系的动态演化过程,最后以浙江省新昌县为例进行实证研究.研究结论显示,根据政企合作创新的互动关系中,区域创新系统演化为初始、离散、整合、协同与集成等五个创新阶段;在地方政府与企业的创新博弈中,地方政府关注的是企业的创新能力与创新动力是否能为本地区创造出大于政府投入的社会效益,而企业是否创新需要在政府支持、技术积累与资金实力的基础上正确考量创新成本与收益作出决策;地方政府由"管家婆"向"店小二"的政府职能转变与企业创新投入-产出的循环累积效应是推动新昌县创新驱动路径的决定因素,而且随着区域创新系统由整合创新向协同创新阶段演化与跃迁,龙头企业开始通过跨国合作或并购构建全球研发中心,形成利用国内外的两种创新资源的集成创新网络.
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