Aiming at the uplink multiuser Multiple Input Multiple Output(MIMO) system,a new algorithm is proposed with the maximum Signal-to-Interference Noise Ratio(SINR) guideline for Multiple Access Interference(MAI) suppression. The algorithm makes full use of the Channel State Information(CSI) to design a filter to suppress multiple access interference caused by multiple access interference and noise. In comparison with Block Diagonalization(BD) algorithm,the proposed algorithm takes the influence of noise into account,and its performance is greatly improved. The algorithm under imperfect channel scenarios is modified, and it exhibits good performance in the simulation results.%针对多用户多输入多输出技术上行传输系统，以最大信干噪比作为多址干扰(MAI)抑制的准则提出了一种新算法。该算法充分利用基站接收端所能获知的信道状态信息构造滤波矩阵，以抑制 MAI以及噪声带来的影响。与广泛关注的块对角化 MAI抑制算法相比，该算法考虑了噪声的影响，性能有较大提升。针对非理想信道环境，给出了本文算法的改进，仿真结果表明该算法具有优异的性能。
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