目的 探讨高密度脂蛋白胆固醇(HDL-C)、血清白蛋白(SA)及C反应蛋白(CRP)在诊断早期重症急性胰腺炎(SAP)中的价值及其临床意义.方法 193例急性胰腺炎(AP)患者分为轻症急性胰腺炎(MAP)组102例和SAP组91例,另选体检健康人群185例作为对照组,检测3组血清HDL-C、SA及CRP水平并进行比较.结果 MAP组和SAP组血清HDL-C、SA水平明显低于对照组(P＜0.05),CRP水平明显高于对照组(P＜0.05);SAP组血清HDLC、SA水平明显低于MAP组(P＜0.05),CRP水平明显高于MAP组(P＜0.05).结论 血清HDL-C、SA和CRP水平的检测对早期诊断SAP具有一定的临床价值.%Objective To investigate the value and clinical significance of high density lipoprotein-cholesterol( HDL-C) ,serum albumin(SA) and C reactive protein(CRP) in the diagnosis of early severe acute pancreatitis( SAP). Methods One hundred and ninety-three patients with acute pancreatitis(AP) were divided into mild acute pancreatitis( MAP) group (n = 102) and SAP group (n =91) , one hundred and eighty-five healthy people were chose as control group. The levels of HDL-C, SA and CRP were detected and compared in three groups. Results Compared with control group,the leveb of HDL-C and SA were lower obviously in MAP group and SAP group (P <0.05) ,but the level of CRP was higher obviously (P < 0.05). Compared with MAP group, the levels of HDL-C and SA were lower obviously in SAP group ( P < 0.05 ) , but the level of CRP was higher obviously(P<0. 05). HDL-C,SA levels in MAP and SAP groups were significantly lower than the control group ( P <0.05) ,CRP levels were significantly higher than the control group( P <0.05). Conclusion HDL-C,SA and CRP levels detecting have certain clinical value to the early diagnosis of SAP.
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