[目的]评价SF-36量表用于炎症性肠病患者生存质量测定的效果。[方法]应用SF-36量表，以自评法对92例炎症性肠病患者的生存质量进行调查。参照国际生存质量评价项目的标准程序，进行信度、效度、区分度和反应度的测试。[结果] SF-36量表的分半信度为0.86，复测信度为0.52-0.86，内部一致性信度为0.74-0.90。因子分析产生的2个主成分，分别代表生理健康和心理健康，累积方差贡献率68.67%。SF-36量表能区分出缓解和活动患者生存质量之间的差异（P<0.01）。反应度试验表明8个维度中4个维度得分和总分对疾病活动指数变化敏感（P<0.05）。[结论] SF-36量表是一份具有较好信度、效度、区分度，一定反应度的生存质量普适性量表，可用于炎症性肠病患者的生存质量评价。% [Objective] To evaluate the effect of measuring quality of life in patients with inflammatory bowel disease by SF-36 scale. [Methods] Ninety-two consecutive patients with inflammatory bowel disease were selected, and completed the SF-36 scales by self-administration. The reliability, validity, discriminant ability and responsiveness were tested according to the standard procedure of the International Quality of Life Assessment Project. [Results] The split-half reliability coefficient of the SF-36 was 0.86, the re-test reliability was 0.52~0.86, the internal consistency reliability was 0.74~0.90. Factor analysis identified two principal components which were a physical factor and a mental factor. They could be used to explain 68.67% of the total variance. The SF-36 scales could discriminate active patients from remission ones(P<0.01). Four of the eight domains and the total score of the SF-36 were respon-sive to the change of the disease activity index(P<0.05). [Conclusion] The SF-36 scale was a reliable, valid and discriminative generic quality of life scale that could be used in inflammatory bowel disease. The responsiveness was not wel enough.
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