Objective To investigate the productive rate of AmpC β-lactamases in the Gram-negative bacilli from the nosocomial infection in Huadong hospital. Methods Durative high expressed AmpC β-lactamases were detected by the improved cefotaxime three-dimensional test. Results The productive rate of the durative high expressed AmpC β-lactamases was 7.20%. In this determination, Enterobacter cloacae, Citrobacter freundii and Serratia marcescens were easy to produce the enzymes, and the productive rates were 36.85%, 33.34% and 33.34% respectively. Conclusions The productive rate of AmpC β-lactamases in the Gram-negative bacilli from the nosocomial infection is rather high, which should be attached great importance to clinic.%目的 了解华东医院的医院感染病原菌中革兰阴性杆菌产AmpC β-内酰胺酶的情况.方法 用改良的头孢西丁三维试验检测持续高产AmpC β-内酰胺酶.结果 华东医院的医院感染病原菌中革兰阴性杆菌产持续高产AmpC β-内酰胺酶的产酶率为7.20%,其中阴沟肠杆菌、弗劳地枸橼酸杆菌和黏质沙雷菌产酶率高,分别为36.85%、33.34%和33.34%.结论 华东医院的医院感染菌株产酶率较高,应引起临床高度重视.
展开▼
