The dimethyl fumarate is extremely widespread in leather application as a antiseptic. But it does great harm to human body. In this paper, the physical and chemical properties of dimethyl fu-marate were summarized. The research progress of dimethyl fumarate in leather products extraction and detection methods was concluded. And it emphasized how to control the dosage of dimethyl fu-marate in order to reduce the harm to human. On this basis, how to develop the new antiseptic to re-place the dimethyl fumarate was prospected.% 富马酸二甲酯（DMF）作为防霉剂在皮革制品中的应用非常广泛，但其对人体的伤害很大。本文总结了富马酸二甲酯的物理化学性质，归纳了皮革制品中富马酸二甲酯的提取及检测方法的研究进展，强调了应该如何控制富马酸二甲酯的用量，以减少其对人体的危害。在此基础上，对开发新的防霉剂来代替富马酸二甲酯的研究前景进行了展望。
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