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When pressure meets light: detecting the photoacoustic effect at the origin

         

摘要

Modern optical microscopy1,including confocal microscopy,twophoton microscopy and optical coherence tomography (OCT),has revolutionized life sciences by providing detailed information of biological samples with cellular and subcellular resolutions,and has become an essential tool for biomedical research labs.However,optical microscopy typically has a limited penetration depth of ~ 1 mm in biological tissue due to strong optical scattering2,3

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