首页> 中文期刊> 《解放军医药杂志》 >原发性血脂异常患者中医体质类型与中医证型相关性研究

原发性血脂异常患者中医体质类型与中医证型相关性研究

         

摘要

Objective To further explore somatotypes and syndrome of patients dyslipidemia, and to analyze the correlation between TCM somatotypes and syndromes through collecting the clinical data so as to provide the basis for pre-vention and treatment of dyslipidemia in clinical practice and improve the clinical efficacy. Methods The TCM somato-types and syndromes of 1008 patients with primary dyslipidemia from medical examination center, clinical service and hospitalization were investigated, and the clinical data and the four diagnostic methods of TCM were collected. The TCM somatotypes were judged according to the Chinese medicine physical endowment classification, and the TCM syndromes were judged according to the scale of clinical syndromes using somatotypes integration, and then the correlation between TCM somatotypes and syndromes was analyzed. Results Among the 1008 patients with primary dyslipidemia, there were 246 patients (24. 4%) with moderate physique quality, 186 cases (18. 5%) with phlegm dampness quality, 169 pa-tients (16. 8%) with Yin deficiency quality, 142 patients (4. 1%) with Qi deficiency quality, 110 patients (10. 9%) with Yang deficiency quality, 52 patients (5. 2%) with bloods stasis quality, 42 patients (4. 2%) with Qi depression quality, 41 patients (4. 1%) with heat-dampness quality and 20 patients (2. 0%) with especial quality. In distribution of TCM syndromes, there were no typical case syndrome in 277 patients (27. 5%), phlegm stagnation syndrome in 225 patients (22. 3%), spleen and kidney Yang deficiency syndrome in 166 patients (16. 5%), Yin deficiency Yang hyper-activities syndrome in 139 patients (13. 8%), liver and kidney Yin deficiency syndrome in 119 patients (11. 8%), and Qi-stagnancy and blood stasis syndrome in 82 patients (8. 1%). The phlegm dampness quality were closely related to phlegm stagnation syndrome and spleen and kidney Yang deficiency syndrome ( P<0. 05 ); Qi deficiency quality were closely related to spleen and kidney Yang deficiency syndrome and no typical case syndrome (P<0. 001, P=0. 001); Yin deficiency syndrome were closely related to liver and kidney Yin deficiency syndrome and Yin deficiency and Yang supfluity syndrome (P<0. 001);Yang deficiency quality were closely related to spleen and kidney Yang deficiency syn-drome (P<0. 001);blood stasis quality were closely related to blood stagnation syndrome (P<0. 001);Qi depression quality were closely related to blood stagnation syndrome and phlegm stagnation syndrome (P<0. 05). Conclusion The main primary dyslipidemia patients are biased type, and the most biased type is phlegm dampness quality. The phlegm stagnation syndrome is the most TCM type of primary dyslipidemia, and common TCM type is no typical case syndrome. The TCM somatotypes are closely related to syndromes in primary dyslipidemia patients.%目的 通过收集血脂异常患者临床资料,进一步探索血脂异常患者体质类型和证型分布规律,分析中医体质类型与中医证型相关性,为辨体与辨证相结合防治血脂异常提供理论依据,提高临床疗效. 方法 从体检中心、门诊和住院人群中筛选出1008例符合原发性血脂异常诊断标准患者,进行中医体质与证型调查,收集其临床资料及中医四诊信息,根据《中医体质分类与判定标准》,判定体质类型,根据中医证候临床调查量表,采用证候积分法,判定中医证候类型,分析中医体质类型与中医证型的相关性. 结果 1008 例原发性血脂异常患者体质构成中平和质246例(24. 4%)、痰湿质186例(18. 5%)、阴虚质169例(16. 8%)、气虚质142例(4. 1%)、阳虚质110例(10. 9%)、血瘀质52例(5. 2%)、气郁质42例(4. 2%)、湿热质41例(4. 1%)、特禀质20例(2. 0%). 证型构成中无典型证277例(27. 5%)、痰浊阻遏证225例(22. 3%)、脾肾阳虚证166例(16. 5%)、阴虚阳亢证139例(13. 8%)、肝肾阴虚证119例(11. 8%)、气滞血瘀证82例(8. 1%). 痰湿质与痰浊阻遏证、脾肾阳虚证密切相关(P<0. 05),气虚质与脾肾阳虚证、无典型证密切相关(P<0. 001,P=0. 001),阴虚质与肝肾阴虚证、阴虚阳亢证密切相关(P<0. 001),阳虚质与脾肾阳虚证密切相关(P<0. 001),血瘀质与气滞血瘀证密切相关(P<0. 001),气郁质与气滞血瘀证、痰浊阻遏证密切相关(P<0. 05). 结论 原发血脂异常患者以偏颇体质为主,痰湿质是最主要的偏颇体质类型. 痰浊阻遏证是最主要的中医证型,无典型证也比较常见. 原发性血脂异常患者中医体质类型与中医证型密切相关.

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