Diabetes mellitus and thyroid dysfunction are the most common endocrine diseases seen in the adult population.Insulin is the only hypoglycemic hormone,while thyroid hormone mediates the level of blood glucose through various ways,including sympathetic nervous system,regulation of glucose transporter and the crosstalk with cortical hormone .The coordination of insulin and thyroid hormone play a crucial role in the main-tenance of the balance of human endocrine.However,this balance can be disrupted by heredity ,autoimmunity and the changes of internal or external environment such as genetic predisposition and infection ,generation of autoantibody and cytokines,thus leading to simultaneous or sequential occurrence of diabetes mellitus and thy-roid diseases,therefore realizing the linkage between the two is particularly significant .%糖尿病和甲状腺功能紊乱是成年人中最常见的内分泌疾病。胰岛素是人体唯一的降血糖激素；甲状腺激素通过交感神经系统、对葡萄糖转运体的调控以及与皮质激素交联参与了血糖的调控，两者相互作用、相互影响，共同维持人体内分泌平衡。然而受遗传、自身免疫、体内外环境变化诸如遗传基因易患性、自身抗体的产生和细胞因子的影响，这种平衡被破坏，导致糖尿病和甲状腺疾病同时或相继出现。因此，如何认识两者之间的联系显得尤为重要。
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