The differentiation of myeloid cells is very important to the establishment of immune system . Under the control of specific growth factors and cytokines, bone marrow hematopoietic stem cells could develop into the myeloblasts and further into the mature granulocytes .According to the molecular weight and cytospin staining,granulocytes can be divided into eosinophils,neutrophils and basophils.In recent years,sig-nificant breakthroughs have been made in the classification definition and developmental differentiation of myeloid cells,providing references for the diagnosis and treatment of blood and immune system diseases.%髓系细胞发育分化对于免疫系统的形成至关重要。在特定生长因子和细胞因子的调控下，骨髓造血干细胞先发育为原粒细胞，进而发育为成熟的粒细胞。根据粒细胞分子量大小和染色情况，可以分为嗜酸粒细胞，中性粒细胞和嗜碱粒细胞。近年来，髓系细胞发育过程的分级定义及其发育调控过程的研究取得了巨大进步，为血液及免疫系统疾病的诊治提供了参考。
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