Objective To compare the application of titanium mesh combined with allograft combined with human bone morphogenetic protein and autogenous bone transplantation in alveolar bone augmentation.Methods A total of 46 cases receiving anterior implant plus alveolar bone increment admitted to Tianmen City First People′s Hospital from Jan.2008 to Dec.2011 were randomly divided into two groups according to random-number table method,group A(n =23) using titanium mesh combined with allograft combined with human bone morphogenetic protein,while group B (n =23) using autogenous bone graft.The alveolar ridge width,the incremental effects and postoperative bone implant stability were compared before and after surgery.Results Postoperative average alveolar ridge width of group A was significantly higher than that of group B [(6.9 ±0.5) mm vs (5.6 ±0.3) mm,P <0.01]; the cure rate of group A was 94.1%,of group B was 60.0%,and the clinical efficacy of group A was better than group B with statistically significant difference (P <0.05); no-loosening rate after 4 months implant was 91.2% in group A,50.6% in group B,the sta-bility of group A was much better than group B,with statistically significant difference(P <0.05).Conclu-sion Titanium mesh combined with allogeneic bone graft combined with human bone morphogenetic protein can significantly increase patient alveolar bone mass and help to stabilize the implant after surgery .%目的：比较钛网结合异体骨移植联合人骨形成蛋白与自体骨移植在种植前牙槽嵴骨增量中的应用效果。方法将2008年1月至2011年12月天门市第一人民医院收治的46例前牙种植并行牙槽嵴骨增量的患者依据随机数字表法分为两组：A 组23例，采用钛网结合异体骨移植联合人骨形成蛋白的方法；B 组23例，采用自体骨移植的方法。比较两组患者手术前后牙槽嵴宽度、骨增量效果及术后种植体稳定性。结果术后 A 组牙槽嵴平均宽度患者显著高于 B 组患者[（6.9±0.5） mm比（5.6±0.3） mm，P ＜0.01]；A 组痊愈率为94.1％，B 组为60.0％，A 组临床疗效优于 B 组，差异有统计学意义（P ＜0.05）；植入种植体4个月，A 组无松动率为91.2％，B 组无松动率为50.6％，A 组稳定性优于 B 组，差异有统计学意义（P ＜0.05）。结论钛网结合异体骨移植和人骨形成蛋白可显著增加患者牙槽嵴骨量，有助于术后种植体的稳定。
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