Objective To investigate the effect of sodium hyaluronate in preventing postoperative intesti-nal adhesion in gastrointestinal perforation operation .Methods A total of 86 patients with gastrointestinal perforation admitted in Beihai People′s Hospital from Jan.2010 to Aug.2012 were selected and according to random number table,they were divided into study group ( n=44 ) and control group ( n =42 ) .Patients in study group were treated with sodium hyaluronate to prevent intestinal adhesion before closing peritoneal . Patients in control group were not treated with any drugs before closing peritoneal.The time of first exhaust, duration of hospital stay and fever were compared between the two groups.Complications and reoperation rate within one year after discharge were also followed up and recorded in two groups.Results The time of first exhaust, duration of hospital stay and fever in study group were significantly shorter than those in control group [(18.2 ±4.7) h vs (29.5 ±5.9) h,(9.5 ±2.4) d vs (15.8 ±3.1) d,(3.2 ±1.3) d vs (5.7 ± 1.8) d].The differences were statistically significant(P<0.01).Incidence of adhesions,bowel obstruction, total complication rate and reoperation rate in study group were 6.8%(3/44),2.3%(1/44),9.1%(4/44),4.5%(2/44), respectively,while those in control group were 21.4%(9/42),7.1%(3/42),28.6%(12/42),16.7%(7/42), respectively.The differences between the two groups were statistically significant (P<0.05).Conclusion Sodium hyaluronate can effectively promote the rehabilitation of patients after operation,reduce the duration of hospital stays and meanwhile prevent the occurrence of postoperative adhe-sions in patients with gastrointestinal perforation .%目的：探讨透明质酸钠对于胃肠穿孔术后患者肠粘连发生的预防效果。方法选取2010年1月至2012年8月北海市人民医院收治的胃肠穿孔患者86例，采用随机数字表法分为研究组（ n＝44）和对照组（n＝42）。研究组在常规关闭腹腔前使用透明质酸钠预防肠粘连，对照组未使用药物直接常规关闭腹腔。比较两组患者术后首次排气时间、住院时间、发热时间；随访并记录患者出院后1年内并发症发生率及再次手术情况。结果研究组患者术后首次排气时间、住院时间及发热时间均显著短于对照组[（18．2±4．7） h 比（29．5±5．9） h、（9．5±2．4） d 比（15．8±3．1） d、（3．2±1．3） d 比（5．7±1．8） d]，差异均有统计学意义（均P＜0．01）；出院后1年内研究组患者肠粘连、肠梗阻、总并发症发生率及再次手术率分别为6．8％（3／44）、2．3％（1／44）、9．1％（4／44）、4．5％（2／44）；对照组分别为21．4％（9／42）、7．1％（3／42）、28．6％（12／42）、16．7％（7／42），两组比较差异均有统计学意义（均P＜0．05）。结论透明质酸钠可促进患者术后康复，缩短住院时间，同时可有效预防患者胃肠穿孔修补术后肠粘连、肠梗阻的发生。
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机译：根据人类病毒（HRSV）和多肽的研究辅助调查结果，氨基酸序列得到了改进，其中包括预防和区域多肽的序列，包括在预防，预防和应用中的序列，在序列中进行预防和应用适用的多肽，包括预防用的此类序列/ a / a / a / a / a / a / a / a / a，a / a / a / a / a / a / a / a / a / a，包括此类序列，用于预防序列（HRSV），用于预防人类多肽
