经前期综合征(PMS)的发病机制十分复杂,目前尚未完全明确,与该病可能相关的神经递质主要包括单胺类、氨基酸类和肽类.国内外已有研究表明PMS与单胺类(以5-羟色胺为主)及氨基酸类(以谷氨酸、氨酪酸为主)神经递质有关,但有关肽类对PMS影响的研究较少较浅.现对可能涉及该病的神经递质及其受体进行归类综述,以期为进一步探讨PMS神经生化方面的微观机制提供参考.%Pathogenesis of premenstrual syndrome is so complicated that a clear understanding of it is still missing. Neurotransmitters,which may have close relation to PMS,including monoamines,aminoacids and neuropeptides. Domestic and abroad researches have found that PMS is closely related to monoamines( 5-HE、 DA and NE )and aminoacids( GABA and Glu are of greater importance ),but studies on neuropeptides are less and supeificial. Here is to introduce the development of neurotransmitters and their receptors related to PMS according to their categories, with expectation to provide references on neural and biochemical micro-mechanism for PMS.
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