首页> 中文期刊> 《海南医科大学学报(英文版)》 >Correlation study of serum Lp-PLA2 and NSE levels with nerve injury degree and lipid metabolism change in patients with acute cerebral infarction

Correlation study of serum Lp-PLA2 and NSE levels with nerve injury degree and lipid metabolism change in patients with acute cerebral infarction

         

摘要

Objective:To study the correlation of serum Lp-PLA2 and NSE levels with nerve injury degree and lipid metabolism change in patients with acute cerebral infarction.Methods: Patients diagnosed with acute cerebral infarction in our hospital between March 2014 and October 2016 were selected as the cerebral infarction group of the study, and healthy subjects receiving physical examination during the same period were selected as control group. Serum was collected to determine the levels of Lp-PLA2 and NSE as well as the content of nerve injury molecules and lipid metabolism molecules.Results:Serum Lp-PLA2, NSE, NO, MDA, LPO, 8-OHdG, ox-LDL, LDL-C and ApoB levels of cerebral infarction group were significantly higher than those of control group while HDL-C and ApoA1 content were significantly lower than those of control group;serum NO, MDA, LPO and 8-OHdG content of patients with NSE>Q3 were significantly higher than those of patients withQ3 were significantly higher than those of patients with

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