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首页> 中文期刊> 《海南医科大学学报(英文版)》 >Effect of Morphine combined with Dezocine on analgesic effect and serum Glu and Cor levels in elderly patients with AD after hip replacement

Effect of Morphine combined with Dezocine on analgesic effect and serum Glu and Cor levels in elderly patients with AD after hip replacement

         
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cqvip:Objective:To observe the analgesic effect of morphine combined with dezocine on elderly patients with AD after hip replacement and the effects of serum Glu and Cor levels.Methods:Totally 120 patients who underwent THR in our hospital from February 2016 to September 2017 were selected as study subjects.They were randomly divided into control group(n=60)and observation group(n=60).The control group was given hydromorphone hydrochloride analgesia after operation,while the observation group was given hydromorphone hydrochloride combined with dezocine for analgesia.The VAS score and Ramsay score of the two groups were observed.The addition of analgesics after operation was compared between the two groups.The levels of inflammatory factors and serum Glu and Cor were measured.The adverse reactions of the two groups were observed.Result:At 48 hours after operation,the VAS score of the observation group was lower than that of the control group(P0.05).In the observation group,the additional use rate of analgesics was 8.33%,which was significantly lower than that of the control group(23.33%,P0.05).The serum Cor and Glu levels in the observation group were significantly lower than those in the control group at 8 hours and 12 hours after operation(P<0.05),and the incidence of adverse reactions in the observation group was 10%,significantly lower than that in the control group(31.67%,P<0.05).Conclusion:Morphine combined with Dezocine can effectively relieve postoperative pain,alleviate inflammation,reduce serum Cor and Glu levels,and reduce the incidence of adverse reactions in elderly patients with AD after hip replacement.It has certain clinical value.

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