Biofilm is a predominant lifestyle for microbes,in which microbial communities adhere to surfaces and are embedded in an extracellular matrix.Regulating the biofilm formation process on surfaces to meet practical demands is of great importance.Herein,we introduced the mechanism of biofilm formation on surfaces along with its key factors.The effects of surface properties,including surface charge,wettability,roughness,topographic patterns,and functional chemical modifications,on bacterial adhesion and biofilm formation were summarized in detail.Finally,we reviewed the research progress in material preparation for inhibiting or enhancing biofilm formation according to different application scenarios.%生物膜是微生物细胞粘附于材料表面的群体性生长方式.在实践应用中,有目的地调控微生物在材料表面的成膜进程具有重要意义.本文概述了生物膜在材料表面的形成机制及其影响因素,综述了材料表面的电荷特征、亲疏水性、形貌模式和功能性化学修饰等物化特性对细胞粘附和生物膜形成的影响,并介绍了目前在不同实际应用场景中抑制成膜和促进成膜材料的研发现状.
展开▼
