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《中国神经再生研究：英文版》
>Chinese herbal extract dl-3n-butylphthalide A commonly used drug for the treatment of ischemic stroke as a novel therapeutic approach to treat neurodegenerative diseases
Chinese herbal extract dl-3n-butylphthalide A commonly used drug for the treatment of ischemic stroke as a novel therapeutic approach to treat neurodegenerative diseases
Dl-3n-butylphthalide is the active component isolated from the seeds of Apium graveolens Linn.A number of pharmacological and clinical studies have proven that dl-3n-butylphthalide is highly potent and multi-targeted with low toxicity and has a long time-window for the treatment of ischemic cerebrovascular disease.The mechanisms underlying dl-3n-butylphthalide include improving mi-tochondrial function and microcirculation,inhibiting apoptosis and reducing oxidative stress.Fur-thermore,dl-3n-butylphthalide may also be promising for the treatment of neurodegenerative dis-eases,such as Alzheimer's disease,vascular dementia and Parkinson's disease.
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